Synthetic biology allows researchers to program cells to perform novel functions such as fluorescing in response to a particular chemical or producing drugs in response to disease markers. In a step toward devising much more complex cellular circuits, MIT engineers have now programmed cells to remember and respond to a series of events. Read […]
The MIT Center for Integrative Synthetic Biology was established and funded in September 2013 as part of the NIH-NIGMS national centers for systems biology. A key feature of CISB is to focus on interdisciplinary and collaborative research into next-generation therapeutics. The MIT-CISB will create the therapeutics of the future by integrating systems biology and synthetic biology. The grant awarded to CISB will enable core group of researchers at MIT to focus on three medically relevant research subjects positioned at the intersection of systems and synthetic biology:
- Cancer therapy
- Artificial tissue homeostasis
- Infectious disease
By integrating top-down systems views of disease with bottom-up synthetic construction of novel treatments, this community will create new disease therapies with the ability to integrate multiple inputs and deliver specific interventions.