Home Page

The MIT Center for Integrative Synthetic Biology was established and funded in September 2013 as part of the NIH-NIGMS national centers for systems biology.  A key feature of CISB is to focus on interdisciplinary and collaborative research into next-generation therapeutics. The MIT-CISB will create the therapeutics of the future by integrating systems biology and synthetic biology. The grant awarded to CISB will enable core group of researchers at MIT to focus on three medically relevant research subjects positioned at the intersection of systems and synthetic biology:

  • Cancer therapy
  • Artificial tissue homeostasis
  • Infectious disease

By integrating top-down systems views of disease with bottom-up synthetic construction of novel treatments, this community will create new disease therapies with the ability to integrate multiple inputs and deliver specific interventions.

News

Public Release: 24-Sep-2015 DARPA awards $32 million contract to MIT, Broad Institute Foundry

Public Release: 24-Sep-2015 DARPA awards $32 million contract to MIT, Broad Institute Foundry

The Foundry, started by MIT biological engineering professor Christopher Voigt and Broad Technology Labs (BTL) director Robert Nicol, is the result of a partnership between BTL and the Synthetic Biology Center of MIT, of which Voigt is co-director. The Foundry enables the rapid design, testing, and fabrication of large sequences of genetic information so they […]

Compound potential

Compound potential

Kristala Jones Prather engineers microbes to produce compounds that can be used in industrial processes efficiently and economically.   MIT News

Viruses join fight against harmful bacteria: Tim Lu

Viruses join fight against harmful bacteria: Tim Lu

Viruses join fight against harmful bacteria Engineered viruses could combat human disease and improve food safety MIT news Article

Mammalian synthetic circuits with RNA binding proteins for RNA-only delivery

Mammalian synthetic circuits with RNA binding proteins for RNA-only delivery

RNA-only multi-input microRNA classifier circuit differentiates between HeLa, HEK293 and MCF7 cells Synthetic regulatory circuits encoded in RNA rather than DNA could provide a means to control cell behavior while avoiding potentially harmful genomic integration in therapeutic applications.  Weiss Lab has created post-transcriptional circuits using RNA-binding proteins, which can be wired in a plug-and-play fashion […]

Upcoming Events

Tue 12

CISB Networking & Coffee Hour

July 12 @ 3:00 pm - 4:00 pm
Second Floor 500 Technology Square Cambridge

Programs

BioBuilder

BioBuilder

BioBuilder puts cutting edge synthetic biology research in the hands of high school teachers and students in the form of teachable modules.

iGEM

iGEM

The International Genetically Engineered Machine (iGEM) Foundation is dedicated to education and competition, advancement of synthetic biology, and the development of open community and collaboration. In 2012, iGEM spun out of MIT and became an independent nonprofit organization located in Cambridge, Massachusetts, USA. The iGEM Foundation fosters scientific research and education through organizing and operating the iGEM […]

OpenWetWare

OpenWetWare

OpenWetWare is an effort to promote the sharing of information, know-how, and wisdom among researchers and groups who are working in biology & biological engineering.

Partners


 

Affiliates


 

 

Top